Poloniex is an established crypto to crypto exchange that is based in the United States. It offers a large selection of tokens to trade and has high liquidity. Poloniex was hacked in 2014, and lost more than 12% of their bitcoin supply. They have improved their security protocols since then. In February, 2018 Poloniex was acquired by Circle, one of the largest crypto payment providers.

Trading Fee: 0%-0.1% Maker and 0%-0.2% Taker
Deposit Fee: Varying Depending on blockchain fees
Withdrawal Fee: Varying Depending on blockchain fees
Number of Tokens/Coins: 97

Bitstamp is one of the most popular fiat to Bitcoin exchanges. It was one of the first big exchanges and it provides customers with a platform that is secure and easy to use. It was originally started in Slovenia but has moved its' operations to Luxembourg.
Bitstamp uses MultiSignature technology for its hot-wallet, as well as a fully insured cold-storage option where kept off-line. They also offer a number of other security features such as two-factor authentication and confirmation emails to enhance account security.
Bitstamp provides the option for limit orders, stop loss, and trailing stop orders. They have an easy to use API that can be integrated into user applications. T
Overall, Bitstamp is a secure and reliable exchange with good liquidity and a solid infrastructure. It is a good option for beginning traders as well as more advanced crypto holders.
Trading Fees: Tiered system depending on volume ranging from 0.1%-025%