Bittrex is one of the largest crypto to crypto exchanges. It offers a large number of trading pairs, but do not allow fiat to crypto trading. Bittrex has one of the largest trading volumes in the market.
It is a reputable exchange with good record on security and is also fully regulated. They provide two factor authentication as well as a number of other options to secure funds. They are United States based and are fully compliant with all laws.
They support more than 190 cryptocurrencies and have a dynamic platform. It’s a good option for both advanced and beginner traders; providing advanced tools like candlestick charts and crosshairs, but with a user-friendly interface that is very intuitive.
Trading Fees: 0.25%

Tokens is developing a cryptocurrency exchange for ERC20 tokens that will be powered by their native Dynamic Trading Rights token. Their exchange places a strong emphasis on community driven governance. They have developed a mechanism that allows DTR token holders to be consulted about the future direction of their trading platform and what additional token pairs will be listed.

BigONE is an exchange that is backed by the blockchain investment firm INBlockchain; an influential investment company that has also invested in EOS, ZCash, Steemit, and other blockchain projects. Several of the companies in INBlockchain's portfolio, that have tokens, are traded on BigOne. BigONE's influential investors give the exchange a high degree of financial stability. The platform is known for its interactive crypto charts and trading tools.

Trading Fee: 0.1%
Withdrawal Fee: 0.002 BTC
Number of Tokens/Coins: 76

BigONE has its own token (BIG) that gives holders a discount on trading fees