Bittrex is one of the largest crypto to crypto exchanges. It offers a large number of trading pairs, but do not allow fiat to crypto trading. Bittrex has one of the largest trading volumes in the market.
It is a reputable exchange with good record on security and is also fully regulated. They provide two factor authentication as well as a number of other options to secure funds. They are United States based and are fully compliant with all laws.
They support more than 190 cryptocurrencies and have a dynamic platform. It’s a good option for both advanced and beginner traders; providing advanced tools like candlestick charts and crosshairs, but with a user-friendly interface that is very intuitive.
Trading Fees: 0.25%

HBTC is a cryptocurrency exchange that was previously known as BHEX, or Blue Helix. The HBTC exchange offers traders a variety of currency pairs, as well as other trading options such as options contracts and and OTC desk. As part of the company's re-branding, a token swap will be held to allow holders to transfer their BHT tokens to HBC.

CoinsBank is a cryptocurrency platform that offers several services, including: a wallet, payment services, and exchange. CoinsBank was formerly known as BIT-X, but underwent a re-branding effort in 2016. The company operates in Scotland but is registered in Belize.

Trading Fee: 0.5%
Withdrawal Fee: 0.001 BTC
Number of Markets: 7

The fees are significantly higher than other exchanges.