Bittrex is one of the largest crypto to crypto exchanges. It offers a large number of trading pairs, but do not allow fiat to crypto trading. Bittrex has one of the largest trading volumes in the market.
It is a reputable exchange with good record on security and is also fully regulated. They provide two factor authentication as well as a number of other options to secure funds. They are United States based and are fully compliant with all laws.
They support more than 190 cryptocurrencies and have a dynamic platform. It’s a good option for both advanced and beginner traders; providing advanced tools like candlestick charts and crosshairs, but with a user-friendly interface that is very intuitive.
Trading Fees: 0.25%

Blockport is a social crypto exchange with a hybrid decentralized architecture. Its social trading features allow users to follow or copy other traders. Traders whose activity is followed are rewarded with Ethereum-based BPT tokens. Token holders also receive discounts on trading fees.

Trading Fees: 0.3%
Withdrawal Fees: 0.0005 BTC, 0.01 ETH

Trade.io is a Switzerland-based financial technology company. Their platform consists of a cryptocurrency exchange and liquidity pool that gives TIOX token holders a share of the revenues that are earned. The company also provides ICO consulting services.