Bittrex is one of the largest crypto to crypto exchanges. It offers a large number of trading pairs, but do not allow fiat to crypto trading. Bittrex has one of the largest trading volumes in the market.
It is a reputable exchange with good record on security and is also fully regulated. They provide two factor authentication as well as a number of other options to secure funds. They are United States based and are fully compliant with all laws.
They support more than 190 cryptocurrencies and have a dynamic platform. It’s a good option for both advanced and beginner traders; providing advanced tools like candlestick charts and crosshairs, but with a user-friendly interface that is very intuitive.
Trading Fees: 0.25%

The Biki Exchange is a cryptocurrency exchange that is based in Singapore and primarily targets Chinese traders. The exchange issued the BIKI token, which provides holders with discounts on trading fees, as well as other benefits.
Trading Fees: 0.15%
Withdrawal Fees: 0.001BTC/per trade and 0.01 ETH / per trade.

HitBTC is an exchange for advanced traders that was founded in 2015. It has one of the largest selection of currency pairings and is a very good exchange for technical traders. Unfortunately, the trading platform has a variety of detailed features that can be intimidating to newer users that aren’t familiar with them.
They have a very good record on security and provide a variety of options to secure accounts, including two factor authentication.
Trading fees vary depending on whether the order is executed immediately or not (.01%-0.1%). There are also no fiat deposit or withdrawal options, making cashing in more difficult.
HitBTC offers a number of trading tools aimed at experienced technical traders. The hundreds of coin pairings and advanced charting tools, allow traders to better take advantage of market opportunities,