BitFinex is a bitcoin to fiat exchange, a margin trading exchange, and a liquidity provider. The platform offers a number of features that expand the financial positions you can take - for example the ability to short Bitcoin via margin trading.
The exchange also offers a set of other cryptos apart from bitcoin such as Litecoin and Ethereum.
Deposits and withdrawals take place via the standard bank transfer means with fees of 0.1% and a minimum of $20. Bitcoin and Litecoin are free.
BitFinex takes security seriously and have moved from a hot wallet cold wallet set up to segregating customer funds where each user has access to their own wallet which they can review on the blockchain.
Bitfinex was hacked on 03 August 2016 and around 120,000 BTC were stolen.
Fee of 0.1% for most trades

BigONE is an exchange that is backed by the blockchain investment firm INBlockchain; an influential investment company that has also invested in EOS, ZCash, Steemit, and other blockchain projects. Several of the companies in INBlockchain's portfolio, that have tokens, are traded on BigOne. BigONE's influential investors give the exchange a high degree of financial stability. The platform is known for its interactive crypto charts and trading tools.

Trading Fee: 0.1%
Withdrawal Fee: 0.002 BTC
Number of Tokens/Coins: 76

BigONE has its own token (BIG) that gives holders a discount on trading fees

TopBTC is an exchange that has received varying reviews. Although TopBTC is known for having large trading volumes, the customer support is lacking and there are a variety of dead coins being traded. The company claims to be from Australia, but unlike other crypto currencies there, it is not a member of the Australian Digital Commerce Association(ADCA). TopBTC has also had many users claim that they were unable to withdraw funds.

Trading Fee: 0.2%
Withdrawal Fee: 0
Number of Tokens/Coins: 26