Truffle is one of the leading providers of blockchain development tools. The Truffle platform consists of three tools that are designed to assist developers in creating DApps: Truffle, Ganache and Drizzle. Truffle is a testing framework for DApps using the Etereum Virtual Machine. Ganache allows users to easily create a personalized version of the Ethereum blockchain to run tests and execute commands. Drizzle is a collection of front-end libraries that help developers create user interfaces for DApps.

FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

Ternio is developing a scalable blockchain framework called Lexicon. It was originally a fork of Hyperledger Fabric, and is designed to handle the high transactions rates that enterprise business clients need. Ternio's framework uses its Lexicon Blockchain as a data protocol, and the Stellar Blockchain as a payment protocol. Ternio will have a Byzantine Fault Tolerance (BFT) consensus mechanism. Ternio's marketing materials mention the benefits that their high performance, Lexicon blockchain can have in programmatic digital advertising, as well as a variety of other industries. Ternio also created the BlockCard; a crypto debit card that enables users to spend their cryptocurrency. Their network is currently powered by the Stellar-based TERN token.