Truffle is one of the leading providers of blockchain development tools. The Truffle platform consists of three tools that are designed to assist developers in creating DApps: Truffle, Ganache and Drizzle. Truffle is a testing framework for DApps using the Etereum Virtual Machine. Ganache allows users to easily create a personalized version of the Ethereum blockchain to run tests and execute commands. Drizzle is a collection of front-end libraries that help developers create user interfaces for DApps.

FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

Algorand is a Boston based company that is developing a blockchain network with a Pure Proof of Stake (PPoS) consensus mechanism. Algorand's decentralized platform is designed to enable faster transaction times and remove some of the technical barriers of creating scalable DApps. Algorand was founded by Silvio Micali, a pioneer in the field of cryptography.