Nethereum is an open source .NET integration library for Ethereum. It is designed to help developers easily integrate the Ethereum blockchain into their .NET applications. It consists of modular libraries for features that are covered are writing smart contracts, cryptographic wallets, DApps, and managing blockchain data.

Truffle is one of the leading providers of blockchain development tools. The Truffle platform consists of three tools that are designed to assist developers in creating DApps: Truffle, Ganache and Drizzle. Truffle is a testing framework for DApps using the Etereum Virtual Machine. Ganache allows users to easily create a personalized version of the Ethereum blockchain to run tests and execute commands. Drizzle is a collection of front-end libraries that help developers create user interfaces for DApps.

Chain is a blockchain software company that creates blockchain-based systems for financial institutions and major companies. They've developed blockchain solutions for companies like Nasdaq, Visa, and Citigroup, as well as a variety of crytpocurrencies. Chain has been successful in incorporating distributed ledger technology in very large and influential companies. Their focus is on using the core innovations of blockchain to improve existing systems. Chain uses blockchain as a software tool that can be applied where it is important for services or product to have more trust, or to build a network without an intermediary