Mainframe is creating a blockchain development platform for decentralized applications. Their marketing materials place a strong emphasis on encryption, privacy, and interoperability. Onyx, a decentralized workplace messaging tool, is the first application to be built on the Mainframe network.
Mainframe is powered by the MFT token.

Universa is developing a customizable blockchain platform that will enable real-time transactions, offline smart contracts, and escrow payments. Their network is currently powered by the Ethereum-based UNTP token.

NEO, formerly known as AntShares, is one of the leading smart contract enabled blockchain platforms that allows for the development of digital assets. Similar to Ethereum, NEO uses two different tokens: NEO and GAS, each of which have a specific purpose on the network. NEO tokens give holders a share in the ownership of the NEO blockchain, and when they are held in a compatible wallet, they are rewarded with GAS tokens. NEO has a Delegated Byzantine Fault Tolerance (dBFT) consensus algorithm that has uses some features of PoS, and is designed to be more scalable than other consensus mechanisms.