FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

Skycoin began as an ambitious infrastructure project aimed at replacing the Proof-of-Work (PoW) and Proof-of-Stake (PoS) consensus algorithms that dominate current blockchain platforms. It has since evolved into a project focused on creating a decentralized mesh-Internet and a platform for other blockchain-based projects. Skycoin is developing an ecosystem with a variety of goals, including: the elimination of mining rewards, development of energy-efficient custom hardware, advancing security and privacy, and achieving transaction speeds that rival current digital payment systems. The ecosystem consists of the native SKY coin, Skywire (decentralized mesh-Internet), Skyminer (hardware and access point for Skywire), Skyledger (decentralized open blockchain network), and a suite of DApps. The consensus algorithm is called Obelisk. The network's nodes agree based on a Web-of-Trust consensus. The ability to influence transaction verification is distributed over the network creating a web of trust. To eliminate mining completely each node on the network connects to a list of nodes that it sees as trustworthy.

Polymath is a blockchain-based protocol that makes it easier to raise capital and create security tokens. The Polymath ST-20 standard embeds regulatory requirements into the tokens themselves, restricting trading to verified participants only. The protocol simplifies the complex technical challenges of creating a security token and aims to bring the multi-trillion dollar financial securities market to the blockchain.