FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

Nethereum is an open source .NET integration library for Ethereum. It is designed to help developers easily integrate the Ethereum blockchain into their .NET applications. It consists of modular libraries for features that are covered are writing smart contracts, cryptographic wallets, DApps, and managing blockchain data.

ChainLink is developing the LINK Network, which will enable connected smart contracts. LINK will provide smart contracts with a variety of external data and access to APIs. ChainLink's goal is to solve the connectivity problem that plagues smart contract based systems, and discourages mass adoption. Many decentralized applications are unable to connect with important external data sources due to limitations involving their consensus protocols. The LINK network wants to connect their smart contracts with external systems and APIs by using secure middleware.