FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

Nethereum is an open source .NET integration library for Ethereum. It is designed to help developers easily integrate the Ethereum blockchain into their .NET applications. It consists of modular libraries for features that are covered are writing smart contracts, cryptographic wallets, DApps, and managing blockchain data.

Algorand is a Boston based company that is developing a blockchain network with a Pure Proof of Stake (PPoS) consensus mechanism. Algorand's decentralized platform is designed to enable faster transaction times and remove some of the technical barriers of creating scalable DApps. Algorand was founded by Silvio Micali, a pioneer in the field of cryptography.