FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

Chain is a blockchain software company that creates blockchain-based systems for financial institutions and major companies. They've developed blockchain solutions for companies like Nasdaq, Visa, and Citigroup, as well as a variety of crytpocurrencies. Chain has been successful in incorporating distributed ledger technology in very large and influential companies. Their focus is on using the core innovations of blockchain to improve existing systems. Chain uses blockchain as a software tool that can be applied where it is important for services or product to have more trust, or to build a network without an intermediary

Nethereum is an open source .NET integration library for Ethereum. It is designed to help developers easily integrate the Ethereum blockchain into their .NET applications. It consists of modular libraries for features that are covered are writing smart contracts, cryptographic wallets, DApps, and managing blockchain data.