FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

Chain is a blockchain software company that creates blockchain-based systems for financial institutions and major companies. They've developed blockchain solutions for companies like Nasdaq, Visa, and Citigroup, as well as a variety of crytpocurrencies. Chain has been successful in incorporating distributed ledger technology in very large and influential companies. Their focus is on using the core innovations of blockchain to improve existing systems. Chain uses blockchain as a software tool that can be applied where it is important for services or product to have more trust, or to build a network without an intermediary

NEO, formerly known as AntShares, is one of the leading smart contract enabled blockchain platforms that allows for the development of digital assets. Similar to Ethereum, NEO uses two different tokens: NEO and GAS, each of which have a specific purpose on the network. NEO tokens give holders a share in the ownership of the NEO blockchain, and when they are held in a compatible wallet, they are rewarded with GAS tokens. NEO has a Delegated Byzantine Fault Tolerance (dBFT) consensus algorithm that has uses some features of PoS, and is designed to be more scalable than other consensus mechanisms.