FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

APEX is building a blockchain infrastructure for consumer applications that will focus on B2C transactions on the internet. Their goal is to provide an enterprise blockchain solution for creating custom DApps that will be used by consumers. The NEO-based network was created by APEX Technologies (formerly Chinapex), an established data technology and AI company. Their network is powered by the NEO-based CPX token.

Polymath is a blockchain-based protocol that makes it easier to raise capital and create security tokens. The Polymath ST-20 standard embeds regulatory requirements into the tokens themselves, restricting trading to verified participants only. The protocol simplifies the complex technical challenges of creating a security token and aims to bring the multi-trillion dollar financial securities market to the blockchain.