FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

APEX is building a blockchain infrastructure for consumer applications that will focus on B2C transactions on the internet. Their goal is to provide an enterprise blockchain solution for creating custom DApps that will be used by consumers. The NEO-based network was created by APEX Technologies (formerly Chinapex), an established data technology and AI company. Their network is powered by the NEO-based CPX token.

Fantom is developing a smart contract platform based on a directed acyclic graph (DAG). They hope to address the scalability issues of current decentralized platforms. Instead of a blockchain, Fantom's Lachesis Protocol uses a directed acyclic graph to confirm transactions asynchronously. This transaction history is immutable and cannot be modified. The platform's Opera Chain will consist of three layers: an application Layer, Opera Ware Layer, and Opera Core Layer. Fanotm issued an Ethereum-based token in 2018.