DAEX is developing a decentralized cryptocurrency clearing ecosystem that will improve the underlying infrastructure of centralized exchanges. DAEX aims to solve many of the security and privacy issues related to centralized cryptocurrency exchanges by providing a secure digital asset storage service for developers and trading platforms. Their ecosystem is powered by the Ethereum-based DAX token.

FLO is a Proof-of-Work blockchain with a metadata layer called floData. It enables users to easily record notes to its blocks, and can be used to create DApps. One of FLO's central features is the Open Index Protocol, which standardizes cryptographic ownership on open networks. The founders of FLO are also working on Alexandria; an open-source standard for users to publish and distribute original content. FLO's source code is based on that of Bitcoin and Litecoin. It is designed to enable fast transactions times.

Blockstream is a private, for profit, blockchain technology company, that has played a key role in helping to develop, and fund, many of the key features of the Bitcoin Core platform. Blockstream is focused on developing bitcoin applications and has raised significant funding from several large investment funds. The company also employs several developers that are very influential within the Bitcoin Core development project. This, as well as being of Bitcoin's largest donors, has led to some criticism about conflicts of interest.
Blockstream is developing a number of Bitcoin applications that are intended to encourage adoption and improve transaction times on the bitcoin network. Their primary focus is on Sidechains, which are are extensions to existing blockchains that improve their functionality. The company is also working closely with industry leaders to create the Bitcoin Lightning system that will support higher trading volume and faster transactions on the bitcoin network. Blockstream is also developing a data feed, satellite network, and other applications that they hope will make blockchain more accessible.