ConsenSys is one of the most influential blockchain technology companies. They are working on a variety of projects to create the infrastructure and applications that will enable scalable adoption of blockchain-based systems. The company's efforts are focused on the Ethereum ecosystem, and include divisions working to advance technology development, establish industry standards, and provide consulting, marketing, and education services.

Chain is a blockchain software company that creates blockchain-based systems for financial institutions and major companies. They've developed blockchain solutions for companies like Nasdaq, Visa, and Citigroup, as well as a variety of crytpocurrencies. Chain has been successful in incorporating distributed ledger technology in very large and influential companies. Their focus is on using the core innovations of blockchain to improve existing systems. Chain uses blockchain as a software tool that can be applied where it is important for services or product to have more trust, or to build a network without an intermediary

APEX is building a blockchain infrastructure for consumer applications that will focus on B2C transactions on the internet. Their goal is to provide an enterprise blockchain solution for creating custom DApps that will be used by consumers. The NEO-based network was created by APEX Technologies (formerly Chinapex), an established data technology and AI company. Their network is powered by the NEO-based CPX token.