Blockstream is a private, for profit, blockchain technology company, that has played a key role in helping to develop, and fund, many of the key features of the Bitcoin Core platform. Blockstream is focused on developing bitcoin applications and has raised significant funding from several large investment funds. The company also employs several developers that are very influential within the Bitcoin Core development project. This, as well as being of Bitcoin's largest donors, has led to some criticism about conflicts of interest.
Blockstream is developing a number of Bitcoin applications that are intended to encourage adoption and improve transaction times on the bitcoin network. Their primary focus is on Sidechains, which are are extensions to existing blockchains that improve their functionality. The company is also working closely with industry leaders to create the Bitcoin Lightning system that will support higher trading volume and faster transactions on the bitcoin network. Blockstream is also developing a data feed, satellite network, and other applications that they hope will make blockchain more accessible.

Fantom is developing a smart contract platform based on a directed acyclic graph (DAG). They hope to address the scalability issues of current decentralized platforms. Instead of a blockchain, Fantom's Lachesis Protocol uses a directed acyclic graph to confirm transactions asynchronously. This transaction history is immutable and cannot be modified. The platform's Opera Chain will consist of three layers: an application Layer, Opera Ware Layer, and Opera Core Layer. Fanotm issued an Ethereum-based token in 2018.

Polymath is a blockchain-based protocol that makes it easier to raise capital and create security tokens. The Polymath ST-20 standard embeds regulatory requirements into the tokens themselves, restricting trading to verified participants only. The protocol simplifies the complex technical challenges of creating a security token and aims to bring the multi-trillion dollar financial securities market to the blockchain.