Primecoin is a cryptocurrency based on finding prime numbers. Identifying prime numbers plays a central role in cryptography. Primecoin's unique Proof-of-Work (PoW) consensus mechanism is able to increase transaction speeds and improve energy efficiency.
The network searches for special prime number chains known as Cunningham chains and bi-twin chains, which are of interest in mathematical research.

Sphere is a smart contract platform and peer-to-peer payment network. The network has a hybrid PoW and PoS consensus mechanism and is powered by the native SPHR token, which can be swapped for an ERC20 token over the Ubiq smart contract platform.

PIRL is a community based blockchain project focused on making cryptocurrencies more accessible. It was the first blockchain to introduce an Ethash-based masternode. Their goal is to develop a comprehensive DApps hosting infrastructure that will be easy to use. Their Poseidon platform is designed to be an on ramp for users without any technical knowledge. PIRL's multi-tiered masternode network has an ASIC-resistant Proof-of-Work (PoW) consensus mechanism, and is powered by the PIRL coin. The company plans on developing features, such as: decentralized file storage, messaging, and escrow services for payments.