The Polkadot blockchain is a multi-chain blockchain that is designed to bundle multiple chains together so that they can be executed in parallel. The goal is for every block on the Polkadot blockchain to contain multiple blocks from other chains. This will enable the network to contain the transaction information from multiple chains and dramatically increase the overall interoperability between different blockchain networks. Polkadot was created by the Web3 Foundation, which is led by Gavin Wood, one of the founders of Ethereum. Polkadot is their flagship project, and aims to solve the issues in the blockchain ecosystem related to disjointed governance and interoperability.

Wanchain is a cross-chain protocol for inter-chain transactions. It was originally a fork of Ethereum, but is now a completely separate blockchain called the WAN chain, that also has a Proof-of-Stake (PoS) consensus mechanism. Wanchain is designed to be a decentralized and interconnected platform to exchange digital assets across separate blockchains. It is meant to connect the growing number of blockchain projects and make them inter-operable.

Metronome is developing a cross-chain cryptocurrency with an emphasis on self-governance. Enable user to transfer value across decentralized platforms. The Metronome network is currently powered by the Ethereum-based MET token.